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Edouard Nice简介

EdouardNice,ProfessorofMonashUniversity,AustraliaHisscientificresearchhaslargelyfocussedonthedevelopmentofnewtechniques(includingmicropreparativeHPLC,biosensoranalysisandproteomics)forthemicro-isolation,purification,characterisationandanalysisofproteinandpeptidegrowthfactors,theirreceptorsandassociatedsignallingmoleculeswiththeaimofunderstandingtheroleofthesemoleculesinneoplasia(inparticularcolorectalcancer(CRC)ManyofthesestudieshavebeenaimedatthediscoveryandcharacterisationofpotentialCRCbiomarkersforearlythedetectionandsurveillanceofthediseaseTothisendhehaspioneeredthefieldofFaecalProteomics,andtheroleofquantitativemassspectrometry(usingthetechniqueofmultiplereactionmonitoring(MRM))forthedevelopmentandvalidationofsensitiveandspecificmultiplexedassaysforusewithpanelsofCRCbiomarkersThisplatformtechnologycanbereadilytranslatedtoothercancers,orotherpathologies(egcardiovasculardisease,diabetes,neuropathology)Hehaspublishedmorethan200peer-reviewedmanuscriptsinhighrankingInternationalJournalsandspecialistjournalsrelatedtohisfieldsofinterestThesearticleshavebeencited

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