李慧英 简介
DrLiisanassistantprofessorattheDavidGeffenSchoolofMedicine,UniversityofCalifornia,LosAngelesShereceivedherBSandMSinbiochemistryfromPekingUniversity,MSinnutritionfromUniversityofCalifornia,Berkeley,andPhDinbiochemistryandmolecularbiologyfromUniversityofCalifornia,LosAngelesHermainresearchinterestistounderstandthehumanmicrobiomeinhealthanddiseaseatbothmolecularandsystemslevelsEachindividualcarriesmanymorebacterialcellsthanhumancellsThemicrobesformanintricatesymbioticsystemwiththehostandplayimportantrolesinhumannutrition,metabolism,andthedevelopmentofimmunesystemCurrentfocusoftheLilabistounderstandtheinteractionsbetweenthemicrobesandthehumanhostinrelationtohumanhealthanddiseasesDrLi’sgroupapplies16SrRNAsequenceanalysis,metagenomicshotgunsequenceanalysis,andmetatranscriptomicanalysisusingNextGenerationhigh-throughputsequencingtechnologiestoextractgenomicandtranscriptionalinformationofboththemicrobesandthehumanhostMolecularbiology,metagenomics,andbioinformaticsarethethreemainareasoftheresearchDrLihasbeenfundedbymultipleinstitutesattheNIHandotherfundingagenciestostudythehumanmicrobiome,includingoneoftheDemonstrationProjectsoftheHumanMicrobiomeProjectShehaspublishedmultiplehigh-impactpeer-reviewedpapersinjournalsincludingScienceTranslationalMedicine,TheISMEJournal,JournalofInvestigativeDermatology,mBio,JournalofAllergyandClinicalImmunology,mSphere