Pentao Liu简介
PentaoLiu,ProfessorofTheWellcomeTrustSangerInstitute,Cambridge,UKDrLiugraduatedfromHenanNormalUniversityandearnedhisMasterofSciencedegreefromChineseAcademyofSciences/UniversityofScienceandTechnologyofChinaAtBaylorCollegeofMedicine,hestudiedmolecularmechanismsofCharcoal-Marie-ToothdiseaseinDrJamesLupski'slaboratoryDrLiureceivedhisPhDfromBaylorCollegeofMedicineundertheguidanceofProfessorAllanBradley,andcompletedhispostdoctoraltrainingatNationalCancerInstitute(USA)inthelaboratoriesofDrNealCopelandandDrNancyJenkinsDrLiujoinedtheWellcomeTrustSangerInstituteinSeptember2003Heinitiatedthehigh-throughputrecombineeringforthelarge-scalemousemutagenesisprogrammeattheSangerInstituteDrLiu'slaboratoryhasidentifiedthecriticalrolesoftranscriptionfactors,Bcl11aandBcl11b,inhematopoieticstemcells,inlymphocytedevelopment,andinmammaryglanddevelopmentBymutatingBcl11b,theyhavediscoveredthatTlymphocytesarereprogrammedtoanewtypeofcancerkillercells,ITNKsDrLiu'slabhasalsoidentifiedthatBCL11Aisanimportantcancergeneintriplenegativebreastcancer