李霞简介
李霞，博士、研究员，博士生导师1985-1995年在河北师范大学生物系获得理学学士和植物生理学硕士学位，并留校任讲师。1995-2001在美国PurdueUniversity生物系和园艺系工作和学习，获得博士学位。2001-2004年在美国VectorTobacco公司任科学家和课题组长。2004年入选中国科学院“百人计划”，回遗传与发育生物学研究所石家庄农业资源研究中心工作。研究方向1、植物抗逆分子机制的研究植物对逆境响应以及抗逆的分子机制是一个重要的生物学问题，涉及到植物在逆境下的可塑性发育、基础代谢以及植物细胞、组织和个体得能量、水分、离子、氧化还原物的稳态的调控等生物学过程。本课题组的研究方向是高等植物逆境生理和分子遗传学。主要包括模式植物拟南芥、小麦和大豆在非生物逆境尤其抗盐碱、干旱和低温条件下的生理和遗传机理。重点是植物根系发育对逆境适应和调控分子网络，逆境条件下植物防御代谢的转换的机制，以及植物生理节水的遗传学基础。最终目标是揭示植物抗逆的分子机理，用遗传转化手段创建抗盐碱和抗旱节水新作物品系。2、大豆固氮效率调控机理的研究大豆是重要的经济作物，是植物蛋白和油脂的主要来源。大豆可以和根瘤菌共生形成根瘤，进而把空气中的N2转化为植物可以利用的NH3。大豆根瘤的发育和固氮效率的高低是影响大豆高产优质的关键因素，二者对环境胁迫非常的敏感。本课题组利用反向遗传学以及转基因等方法对大豆根瘤发育和固氮效率对非生物胁迫响应的分子机制进行系统性研究。重点研究大豆miRNA及靶基因影响大豆根瘤发育和固氮效率的分子调控网络。发表文章（*通讯作者）WangY,LiK,ChenL,ZouY,LiuH,TianY,LiD,WangR,ZhaoF,FergusonB,GresshoffP,LiX*(2015)MicroRNA167-directedregulationoftheauxinresponsefactors,GmARF8aandGmARF8b,isrequiredforsoybean(GlycinemaxL)nodulationandlateralrootdevelopmentPlantPhysiologyDOI:101104/pp1500265WangY,WangL,ZouY,ChenL,CaiZ,ZhangS,ZhaoF,TianY,JiangQ,FergusonB,GresshoffP,LiX*(2014)SoybeanmiR172ctargetstherepressiveAP2transcriptionfactorNNC1toactivateENOD40expressionandregulatenoduleinitiationPlantCell26:4782-4801JiH,WangS,LiK,SzakonyiD,KonczC,LiX*(2014)PRL1modulatesrootstemcellnicheactivityandmeristemsizethroughWOX5andPLTsinArabidopsisPlantJournal81:399-412JiH,LiuL,LiK,XieQ,WangZ,ZhaoX,LiX*(2014)PEG-mediatedosmoticstressinducesprematuredifferentiationoftherootapicalmeristemandoutgrowthoflateralrootsinwheatJournalofExperimentalBotany65:4863-4872KongD,LiM,DongZ,JiH,LiX*(2014)IdentificationofTaWD40D,awheatWD40repeat-containingproteinthatisassociatedwithplanttolerancetoabioticstressesPlantCellReport34:395-410ZhangS,WangY,LiK,ZouY,ChenL,LiD,CaiZ,WangL,WangR,WangY,LiX*(2014)UncoveringmiRNA-mediatedresponsestolowtemperatureinnitrogen-fixingnodulesofsoybeanInternationalJournalofMolecularSciences15:13596-13614LiuL,GuoG,WangZ,JiH,MouF,LiX*(2014)AuxininplantgrowthandstressresponsesIn:Lam-SonPhanTranandSikanderPal(eds)Phytohormones:Awindowtometabolism,signalingandbiotechnologicalapplicationSpringerScience,NewYork,USA,pp1-35LiD,LiuH,QiaoY,WangY,CaiZ,DongB,ShiC,LiuY,LiX,LiuMengyu(2013)EffectsofelevatedCO2onthegrowth,seedyield,andwateruseefficiencyofsoybean(Glycinemax(L)Merr)underdroughtstressAgriculturalWaterManagement129:105-112ZouY,WangY,WangL,YangL,WangR,LiX*(2013)miR172bcontrolsthetransitiontoautotrophicdevelopmentinhibitedbyABAinArabidopsisPLoSONE23:e64770LuoY,WangZ,JiH,FangH,WangS,TianL,LiX*(2013)AnArabidopsishomologofimportinbeta1isrequiredforABAresponseanddroughttolerancePlantJournal75:377-389DongZ,ShiL,WangY,ChenL,CaiZ,WangY,JinJ,LiX*(2013)IdentificationanddynamicregulationofmicroRNAsinvolvedinsaltstressresponsesinfunctionalsoybeannodulesbyhigh-throughputsequencingInternationalJournalofMolecularSciences14:2717-2738PengY,MaW,ChenL,YangL,LiS,ZhaoH,ZhaoY,JinW,LiN,BevanMW,LiX,TongY,LiY(2013)ControlofrootmeristemsizebyDA1-relatedprotein2inArabidopsisthalianaPlantPhysiology16:1542-1556ZhaoH,LiuL,MoH,QianL,CuiS,LiX,MaL(2013)TheATP-bindingcassettetransporterABCB19regulatespostembryonicorganseparationinArabidopsisPLoSONE8:e60809JiH,PardoJM,BatelliG,VanOostenMJ,BressanRA,LiX*(2013)Thesaltoverlysensitive(SOS)pathway:establishedandemergingrolesMolecularPlant6:275-286ZhaoH,WangX,ZhuD,CuiS,LiX,CaoY,MaL(2012)AsingleaminoacidsubstitutioninIIIfsubfamilyofbasicHelix-Loop-HelixtranscriptionfactorAtMYC1leadstotrichomeandroothairpatterningdefectsbyabolishingitsinteractionwithpartnerproteinsinArabidopsisJournalofBiologicalChemistry287:14109-14121HaoL,WangW,ChenC,WangY,LiuT,LiX,ShangZ(2012)ExtracellularATPpromotesstomatalopeningofArabidopsisthalianathroughheterotrimericGproteinasubunitandreactiveoxygenspeciesMolecularPlant5:852-864ZhaoY,WangT,ZhangW,LiX*(2011)SOS3mediateslateralrootdevelopmentunderlowsaltstressthroughregulationofauxinredistributionandmaximainArabidopsisNewPhytologist189:1122-1134CaoM,LiX*(2010)Dieforlivingbetter:PlantsmodifyrootsystemarchitecturethroughinducingPCDinrootmeristemunderseverewaterstressPlantSignaling